酒的起源.ppt

,,酒的起源,杜康造酒說上天造酒說儀狄造酒說猿猴造酒說,Theusageofethanol,AdditionalRemarks,酒精燈燃料。防凍劑運用酒精較低冰點特性。消毒劑改變生物體蛋白質特性與溶解期酯質。麻醉藥酒精直接作用在神經細胞膜上﹐如同麻醉藥，當作抑制劑。,AdditionalRemarks,化妝品、香水如花露水酒精本身易溶於水且亦是良好的溶劑。殺蟲劑香蕉水為乙酸乙酯CH3COCH2COOC2H5由乙醇生成，酒精是有機物體的良好溶劑，香蕉水用來調稀油漆。,Pathwaysinvolvedinsynthesisofethanol,Glycolysis,Transportofglucose,Ethanoldegradation,Mixedacidfermentation,,,,,缺少pyruvatedecarboxylasealcoholdehydrogenase,調節磷酸果糖激酶烯醇酶,E.coliK-12MG1655pathway,,Transportofglucose,EC2.7.1.69,PTSPhosphoTransferaseSystemsystemEIIManptsI,ptsH,manX,manY,manZglucosamine,β-D-glucose,N-acetyl-D-glucosamine,mannose,fructoseEIIGlcptsI,ptsH,crr,ptsGβ-D-glucoseNeedMg2undernormalphysiologicalconditions,EIIGlc,Glycolysis-I,,Mixedacidfermentation-partial,Inananaerobicenvironment,Glycolysis-II,,Ethanoldegradation,InGluconeogenesis,基因的選擇,大量的製造（BacteriaTransation）,,得到大量Plasmids,,PCR,,InVitroTranscription,,DNA,,RNA,,,保存菌種,Geneselection,Whatisimportant,大量的製造（BacteriaTransation）,GEEPE,大量的製造（BacteriaTransation）,,MTBE甲基第三丁基醚,化學式CH33COCH3兩派說法致癌物非致癌物,Reference,http//biocyc.org/ECOLI/EcoCychttp//www.genome.jp/kegg/KEGGhttp//www.chem.mtu.edu/drshonna/cm4710/lectures/molecularbiotech2.pdf,2004/11/12.,